Leukopaks
Research & GMP Grade
Extracted peripheral blood via apheresis with concentrated levels of T cells, B cells, NK cells, monocytes, and CD34+ cells
Why choose Precision Leukopaks?
Donor Recallability
Recall donors with your desired characteristics to optimize your results.
Same-Day Delivery
The location of our apheresis center allows for same day delivery to Greater Boston, and next-day delivery across the United States.
Same-Day Processing
Our on-site immunology lab allows for a quick turnaround from collection to processing, ensuring high cell viabilities.
Customizable Product
From donor selection to processing, cell isolations, and shipping—our leukopaks are made to fit your needs.
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Curated Leukopaks for your research needs
The benefits of Precision leukopaks begin with our CLIA-certified, FDA-registered apheresis collection center, allowing for customization of your product from donor identification to delivery. Donor demographics, HLA type, and phenotype can be selected based on your criteria. Our in-house immunology laboratory allows for custom cellular processing of leukopaks into PBMCs, or other isolated cell lines upon request.
Pre-freeze viability
Choosing the right Leukopak for your research
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Fresh Leukopaks
These leukopaks are collected from healthy donors before being shipped fresh for swift use - eliminating the need for freezing or storing them.
Because the cells are shipped fresh, they're used for short-term applications and experiments.Benefits
- Get prompt shipments of cells ready for isolation
- Eliminate the need to freeze cells, translating to high viability and functionality
- Preserve specific cell subsets and delicate characteristics
Drawback
- A missed or late shipment could mean losing all viability
- The short timeline can cause logistical challenges and potentially increase costs
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Cryopreserved Leukopaks
As the name suggests, cryopreserved leukopaks are frozen at ultra-low temperatures to preserve the sample cells for extended periods of time.
The cryopreservation and thawing processes result in minimal viability loss while providing more flexibility in shipment schedules and experimentation timelines.Benefits
- Extend your experimental window by storing samples until you need them
- Improve batch consistency and reproducibility with preserved, standardized cell samples
Drawback
- Freezing and thawing processes can lead to cell loss
- Thawing and recovery time may delay research or application timelines
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Mobilized Leukopaks
Mobilized leukopaks are collected from donors who were treated with a drug that stimulates an increased release of stem cells from the bone marrow into circulation.
The increased concentration of stem and progenitor cells in mobilized leukopaks is ideal for cell therapy and research applications.Benefits
- Acquire the highest concentration of CD34+ stem cells up to 10x more than in normal leukopaks
- 2-4x more total cell yields than in normal leu
- Enhance reproducibility with a consistent supply of cells from a single donor
Drawback
- Mobilized leukopaks tend to cost more than normal leukopak products, but the benefits outweigh the costs
Leukopaks are collected from our database of deeply characterized donors, providing detailed information
- Demographics
- Medical history, disease characterization, outcome data, CBC report available, all viral negative and vaccination status captured
- Immunophenotyping via flow cytometry
- Recallable, HLA- typed donors
- Custom donor specifications upon request
Donors undergo an initial screening process prior to their first donation and are then prescreened every 3 months to ensure they meet our donation standards.
Precision’s Leukopaks are collected at our in-house Apheresis Center
Located in the Greater Boston Area
Our in-house, CLIA-certified Apheresis Donor Center is fully equipped with the Spectra Optia® Apheresis System and a staff of experienced nurses and scientific experts. We collect leukopaks from healthy and disease-state donors that are customizable from donor to delivery – to meet your research needs.
On-Site Rapid Sample Analysis for Leukopaks
In conjunction with our in-house apheresis center, we have an on-site immunology lab dedicated to rapid analysis and processing of samples.
Immunophenotyping panels via flow cytometry
- Purity assessment on isolated cell subsets
- Custom panels available
ELISpot/Fluorospot sample analysis
- IFN-γ immune responses
- Custom assays available
Cell culture
- PBMCs, BMMCs, DTCs
- T-cell expansion
- Enriched cell populations
CBC analysis
- 5-part differential
ELISA
- AV serotype assays
- Custom assays available
In addition, Precision has a full-suite of global specialty lab services offering in-depth analysis for your samples
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PBMC & Sample Processing
Sample processing with expertise in PBMC isolations from labs across 5 continents
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Flow Cytometry
Standard and spectral flow cytometry, on both research-grade and CLIA-validated instruments -
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Cell-Based Assays
Developing and qualifying 2D and 3D human in vitro cell-based models using a broad range of human primary cell types, with analysis enabling a variety of endpoints
